Mitochondrial Cytochrome c Oxidase Subunit 1 Sequence Variation in Prostate Cancer
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چکیده
منابع مشابه
Mitochondrial Cytochrome c Oxidase Subunit 1 Sequence Variation in Prostate Cancer
PURPOSE Mitochondrial DNA (mtDNA) gene mutations have been described in nearly every adult solid neoplasm including prostate cancer. There are marked racial differences in specific inherited mutations within the cytochrome c oxidase subunit 1 (COI) gene in individuals with prostate cancer (PCa). The purpose of this study was to identify the variation in COI gene sequence in prostate cancer pati...
متن کاملSequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men.
BACKGROUND Previous studies have found associations between mitochondrial DNA (mtDNA) mutations and several cancer types. Recently, we found that mutations in the mtDNA gene cytochrome c oxidase subunit 1 (COI) were both linked to and associated with prostate cancer (PCa) in Caucasian men. Here we examine the association between COI mutations and PCa in African American men. METHODS The entir...
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Background: Gamete cryopreservation is an inseparable part of assisted reproductive technology, and vitrification is an effective approach to the cryopreservation of oocytes. The aim of this study was to investigate vitrification effects on the expression levels of mitochondrial transcription factor A (Tfam) and mitochondrial-encoded cytochrome c oxidase subunit 1 (Cox1) in mouse metaphase II o...
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In the current study, Mitochondrial Cytochrome c oxidase gene especially codons within subunit 1 (cox1) of H. diminuta and H. nana Egyptian isolates from two stages (adult worms and eggs) and hosts origin (human and rat) were amplified, sequenced and aligned. PCR products were approximately 700 bp, 702 bp and 715 bp of H. nana rat isolates, H. diminuta rat isolates, and H. nana human isolates, ...
متن کاملComparison of Mitochondrial-Related Transcriptional Levels of mitochondrial transcription factor A, Nuclear respiratory factor 1 and cytochrome c oxidase subunit 1 Genes in Single Human Oocytes at Various Stages of the Oocyte Maturation
Background: The aim of the current study was to assess the mRNA levels of two mitochondria-related genes, including nuclear-encoded NRF1 (nuclear respiratory factor 1), mitochondrial transcription factor A (TFAM), and mitochondrial-encoded cytochrome c oxidase subunit 1 (MT-CO1) genes in various stages of the human oocyte maturation. Methods: Oocytes were obtained from nine infertile women wit...
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ژورنال
عنوان ژورنال: Scientifica
سال: 2012
ISSN: 2090-908X
DOI: 10.6064/2012/701810